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Modeling hepatic insulin sensitivity during a meal: validation against the euglycemic hyperinsulinemic clamp

Por Dalla Man, Chiara, Piccinini, Francesca, Basu, Rita, Basu, Ananda, Rizza, Robert A., Cobelli, Claudio
Publicado em 2013

“..., S(I)(Lmeal) has never been compared directly with its euglycemic hyperinsulinemic clamp counterpart...”
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Patch-clamp recording of amino acid-activated responses in "organotypic" slice cultures.

Por Llano, I, Marty, A, Johnson, J W, Ascher, P, Gähwiler, B H
Publicado em 1988

“...Patch-clamp recording techniques were used to study the properties of amino acid-activated channels...”
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Resurgent Na(+) current in pyramidal neurones of rat perirhinal cortex: axonal location of channels and contribution to depolarizing drive during repetitive firing

Por Castelli, Loretta, Biella, Gerardo, Toselli, Mauro, Magistretti, Jacopo
Publicado em 2007

“... II). Patch-clamp experiments in acute PRC slices were first carried out. A measurable I(NaR...”
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Mitochondrial Patch-Clamp of Beige Adipocytes Reveals UCP1-positive and UCP1-negative Cells Both Exhibiting Futile Creatine Cycling

Por Bertholet, Ambre M., Kazak, Lawrence, Chouchani, Edward T., Bogaczyńska, Marta G., Paranjpe, Ishan, Wainwright, Gabrielle L., Bétourné, Alexandre, Kajimura, Shingo, Spiegelman, Bruce M., Kirichok, Yuriy
Publicado no Cell Metab (2017)

“... direct comparison of their thermogenic H(+) leak (I(H)). All inguinal beige adipocytes had robust UCP1...”
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Inhibition of human α7 nicotinic acetylcholine receptors by open channel blockers of N-methyl-D-aspartate receptors

Por Maskell, Peter D, Speder, Pauline, Newberry, Nigel R, Bermudez, Isabel
Publicado em 2003

“... on this receptor were examined using two-electrode voltage-clamp recordings and (125)I-α-bungarotoxin ((125)I-α...”
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Oxytocin Modulates Glutamatergic Synaptic Transmission between Cultured Neonatal Spinal Cord Dorsal Horn Neurons

Por Jo, Young-Hwan, Stoeckel, Marie-Elisabeth, Freund-Mercier, Marie-José, Schlichter, Rémy
Publicado no J Neurosci (1998)

“... by radioautography in laminae I and II of the dorsal horn (DH) and on cultured neonatal DH neurons were studied...”
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Distribution of cardiac sodium channels in clusters potentiates ephaptic interactions in the intercalated disc

Por Hichri, Echrak, Abriel, Hugues, Kucera, Jan P.
Publicado no J Physiol (2018)

“... significance of these clusters has never been investigated. In patch clamp experiments with HEK cells stably...”
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Dual modulation of K+ currents and cytosolic Ca2+ by the peptide TRH and its derivatives in guinea-pig septal neurones.

Por Toledo-Aral, J, Castellano, A, Ureña, J, López-Barneo, J
Publicado em 1993

“... under whole-cell patch clamp can generate two major K+ currents: (i) a fast and transient K+ current (I...”
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Hyperpolarizing muscarinic responses of freshly dissociated rat hippocampal CA1 neurones.

Por Wakamori, M, Hidaka, H, Akaike, N
Publicado em 1993

“... Ca2+ ([Ca2+]i) was fluorometrically measured using fura-2. 2. In current clamp conditions, ACh...”
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Novel Metabolic Disorders in Skeletal Muscle of Lipodystrophic Bscl2/Seipin Deficient Mice

Por Xu, Wenqiong, Zhou, Hongyi, Xuan, Hongzhuan, Saha, Pradip, Wang, Gongxian, Chen, Weiqin
Publicado no Mol Cell Endocrinol (2018)

“... metabolism in skeletal muscle have never been investigated. Here, we identified Bscl2(−/−) mice displayed...”
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Region-Specific Developmental Specialization of GABA–Glycine Cosynapses in Laminas I–II of the Rat Spinal Dorsal Horn

Por Keller, A. Florence, Coull, Jeffrey A. M., Chéry, Nadège, Poisbeau, Pierrick, De Koninck, Yves
Publicado no J Neurosci (2001)

“... recorded mIPSCs using patch-clamp techniques in lamina I–II neurons in spinal slices taken at different...”
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The Rate- and Species-Dependence of Short-Term Memory in Cardiac Myocytes

Por Tolkacheva, Elena G.
Publicado em 2007

“... in general, and the onset of irregular cardiac rhythm in particular, its has never been adequately quantified...”
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Properties of Layer 6 Pyramidal Neuron Apical Dendrites

Por Ledergerber, Debora, Larkum, Matthew Evan
Publicado no J Neurosci (2010)

“... terminates in layer 4 rather than layer 1. Like layer 5 pyramidal neurons, they participate in a feedback...”
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Modulation of the delayed rectifier potassium current in frog cardiomyocytes by beta-adrenergic agonists and magnesium.

Por Duchatelle-Gourdon, I, Hartzell, H C, Lagrutta, A A
Publicado em 1989

“... contained 1 mM [Mg2+]. In contrast, when the solution contained 0.3 mM [Mg2+], rundown was almost never...”
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Transient inward current in guinea-pig atrial myocytes reflects a change of sodium-calcium exchange current.

Por Lipp, P, Pott, L
Publicado em 1988

“...1. Enzymatically isolated, cultured myocytes from hearts of adult guinea-pigs were voltage clamped...”
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Neuronal nicotinic acetylcholine receptor currents in phaeochromocytoma (PC12) cells: dual mechanisms of rectification.

Por Sands, S B, Barish, M E
Publicado em 1992

“...1. Neuronal nicotinic acetylcholine receptor (nAChR) currents in PC12 cells were studied using...”
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Serotonin inhibits Ca2+ currents in porcine melanotrophs by activating 5-HT1C and 5-HT1A receptors.

Por Ciranna, L, Mouginot, D, Feltz, P, Schlichter, R
Publicado em 1993

“...1. We have investigated the effect of serotonin (5-HT) on Ca2+ currents in cultured porcine...”
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Alpha 1-adrenoceptor activation of a non-selective cation current in rabbit portal vein by 1,2-diacyl-sn-glycerol.

Por Helliwell, R M, Large, W A
Publicado em 1997

“...1. The transduction mechanisms involved in the activation and modulation of the noradrenaline...”
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Voltage-clamp experiments on frog single skeletal muscle fibres: evidence for a tubular sodium current.

Por Mandrino, M
Publicado em 1977

“...1. A late inward current following the initial sodium current is sometimes observed on frog single...”
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Unprecedented high insulin secretion in a healthy human subject after intravenous glucagon-like peptide-1: a case report

Por Knop, Filip K, Lund, Asger, Madsbad, Sten, Holst, Jens J, Krarup, Thure, Vilsbøll, Tina
Publicado em 2014

“... insulinotropic in strictly glucose-dependent fashions and glucagon-like peptide-1 is often referred to as one...”
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