Resultados da pesquisa - (( drug modes novel ther ) OR ((( drug leads develop them ) OR ( drug disease developed type ))))*

1

Por Kitamoto, Tetsuyuki., International Symposium of Prion Diseases for Food and Drug Safety
Publicado em 2005

“... (vCJD) in the United Kingdom. In 2004, the International symposium of prion diseases for food and drug...”
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Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A

Por Long, Yan, Xu, Miao, Li, Rong, Dai, Sheng, Beers, Jeanette, Chen, Guokai, Soheilian, Ferri, Baxa, Ulrich, Wang, Mengqiao, Marugan, Juan J., Muro, Silvia, Li, Zhiyuan, Brady, Roscoe, Zheng, Wei
Publicado no Stem Cells Transl Med (2016)

Assuntos: “...Cell-Based Drug Development, Screening, and Toxicology...”
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A standardised framework to identify optimal animal models for efficacy assessment in drug development

Por S. Ferreira, Guilherme, Veening-Griffioen, Désirée H., Boon, Wouter P. C., Moors, Ellen H. M., Gispen-de Wied, Christine C., Schellekens, Huub, van Meer, Peter J. K.
Publicado no PLoS One (2019)

“... and unnecessary attrition in drug development. OBJECTIVES: To develop a tool to assess, validate and compare...”
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Medulloblastoma Drugs in Development: Current Leads, Trials and Drawbacks

Por Wen, Jiachen, Hadden, M. Kyle
Publicado no Eur J Med Chem (2021)

“..., the development of targeted therapies for MB has also increased. Targeted drugs have shown unique privileges over...”
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Alkaloids from Marine Invertebrates as Important Leads for Anticancer Drugs Discovery and Development

Por Imperatore, Concetta, Aiello, Anna, D’Aniello, Filomena, Senese, Maria, Menna, Marialuisa
Publicado no Molecules (2014)

“... state of the potential and/or development of some of them as new drugs, as well as the current knowledge...”
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Latest drug developments in the field of cardiovascular disease

Por Stern, Craig S, Lebowitz, Jason
Publicado em 2010

“... of the models is illustrative of the types of approaches being used to develop new cardiovascular agents....”
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Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis

Por Hunter Kerry, Hölscher Christian
Publicado em 2012-03-01

Assuntos: “...Alzheimer disease...”
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New and Future Drug Development for Gastroesophageal Reflux Disease

Por Maradey-Romero, Carla, Fass, Ronnie
Publicado em 2014

“... numerous areas of unmet needs in GERD. Drug development has been focused on potent histamine type 2...”
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Drug Development for Nonalcoholic Fatty Liver Disease: Landscape and Challenges

Por Thiagarajan, Prarthana, Aithal, Guruprasad P.
Publicado no J Clin Exp Hepatol (2019)

“...Nonalcoholic fatty liver disease (NAFLD) is now the leading cause of chronic liver disease...”
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Protein Kinases as Drug Development Targets for Heart Disease Therapy

Por Alison L. Müller, Naranjan S. Dhalla
Publicado em 2010-07-01

“... for drug development for therapy of heart disease....”
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Protein Kinases as Drug Development Targets for Heart Disease Therapy

Por Dhalla, Naranjan S., Müller, Alison L.
Publicado em 2010

“... targets for drug development for therapy of heart disease....”
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Alzheimer’s Disease Drug Development in 2008 and Beyond: Problems and Opportunities

Por Becker, Robert E., Greig, Nigel H.
Publicado em 2008

“... current drug development practices ready to impact other AD drug development [1]. To identify and counter...”
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1341. Development of a Series of High-Throughput Screens to Identify Leads for Nontuberculous Mycobacteria Drug Design

Por McGuffin, Sarah, Mullen, Steven, Early, Julie, Parish, Tanya
Publicado no Open Forum Infect Dis (2019)

“... usurps advances made in TB drug development and leverages them for NTM drug discovery. This will help...”
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Human α-Galactosidase A Mutants: Priceless Tools to Develop Novel Therapies for Fabry Disease

Por Modrego, Andrea, Amaranto, Marilla, Godino, Agustina, Mendoza, Rosa, Barra, José Luis, Corchero, José Luis
Publicado no Int J Mol Sci (2021)

“... their putative application for the development of novel drugs for the treatment of FD. Unfavorable mutants...”
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Bleeding by Bruton Tyrosine Kinase-Inhibitors: Dependency on Drug Type and Disease

Por von Hundelshausen, Philipp, Siess, Wolfgang
Publicado no Cancers (Basel) (2021)

“...-cell malignancies and in development against various autoimmune diseases, but they have been also...”
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Effect of Psychotropic Drugs on Development of Diabetes Mellitus in Patients With Alzheimer's Disease

Por Chang, Ki Jung, Hong, Chang Hyung, Lee, Yunhwan, Lee, Kang Soo, Roh, Hyun Woong, Back, Joung Hwan, Jung, Young Ki, Lim, Ki Young, Noh, Jai Sung, Kim, Hyun Chung, Choi, Seong Hye, Kim, Seong Yoon, Na, Duk L., Seo, Sang Won, Lee, Soojin, Son, Sang Joon
Publicado no Medicine (Baltimore) (2015)

“... receiving 3 types of psychotropic drugs, that is, antipsychotics, antidepressants, and sedative anxiolytics...”
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Ginger components as new leads for the design and development of novel multi-targeted anti-Alzheimer’s drugs: a computational investigation

Por Azam, Faizul, Amer, Abdualrahman M, Abulifa, Abdullah R, Elzwawi, Mustafa M
Publicado em 2014

“... promising drug candidates for the treatment of Alzheimer’s disease....”
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Coronavirus Disease (COVID-19): Current Status and Prospects for Drug and Vaccine Development

Por Ita, Kevin
Publicado no Arch Med Res (2021)

“.... This review focuses on the drugs and vaccines being developed against the COVID-19....”
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Aggressive treatment in paediatric or young patients with drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is associated with future development of type III polyglandular autoimmune syndrome

Por Morita, Chiyo, Yanase, Tetsuji, Shiohara, Tetsuo, Aoyama, Yumi
Publicado no BMJ Case Rep (2018)

Assuntos: “...Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect...”
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Strategies for the Development of Conotoxins as New Therapeutic Leads

Por Brady, Ryan M., Baell, Jonathan B., Norton, Raymond S.
Publicado em 2013

“... and selectivity, making them attractive leads for therapeutic development. In some cases the native peptide...”
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