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Alzheimer’s Disease Drug Development in 2008 and Beyond: Problems and Opportunities

Recently, a number of Alzheimer’s disease (AD) multi-center clinical trials (CT) have failed to provide statistically significant evidence of drug efficacy. To test for possible design or execution flaws we analyzed in detail CTs for two failed drugs that were strongly supported by preclinical evide...

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Detalhes bibliográficos
Main Authors: Becker, Robert E., Greig, Nigel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570097/
https://ncbi.nlm.nih.gov/pubmed/18690832
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