Animal Models That Best Reproduce the Clinical Manifestations of Human Intoxication with Organophosphorus Compounds

Por Pereira, Edna F. R., Aracava, Yasco, DeTolla, Louis J., Beecham, E. Jeffrey, Basinger, G. William, Wakayama, Edgar J., Albuquerque, Edson X.
Publicado em 2014

Timosaponin B-II ameliorates diabetic nephropathy via TXNIP, mTOR, and NF-κB signaling pathways in alloxan-induced mice

Por Yuan, Yong-Liang, Guo, Chang-Run, Cui, Ling-Ling, Ruan, Shi-Xia, Zhang, Chun-Feng, Ji, De, Yang, Zhong-Lin, Li, Fei
Publicado no Drug Des Devel Ther (2015)

Exploratory study on the impact of switching to nilotinib in 18 patients with chronic myeloid leukemia in chronic phase with suboptimal response to imatinib

Por Ailawadhi, Sikander, Akard, Luke P., Miller, Carole B., Jillella, Anand, DeAngelo, Daniel J., Ericson, Solveig G., Lin, Felice, Warsi, Ghulam, Radich, Jerald
Publicado no Ther Adv Hematol (2016)

Clinical dosing regimen of selinexor maintains normal immune homeostasis and T cell effector function in mice: implications for combination with immunotherapy

Por Tyler, Paul M., Servos, Mariah M., de Vries, Romy C., Klebanov, Boris, Kashyap, Trinayan, Sacham, Sharon, Landesman, Yosef, Dougan, Michael, Dougan, Stephanie K.
Publicado no Mol Cancer Ther (2017)

Neuroprotective Efficacy and Pharmacokinetic Behavior of Novel Anti-Inflammatory Para-Phenyl Substituted Diindolylmethanes in a Mouse Model of Parkinson’s Disease

Por De Miranda, Briana R., Miller, James A., Hansen, Ryan J., Lunghofer, Paul J., Safe, Stephen, Gustafson, Daniel L., Colagiovanni, Dorothy, Tjalkens, Ronald B.
Publicado no J Pharmacol Exp Ther (2013)

Predictive performance of gentamicin dosing nomograms

Por Lee, Jieon, Yoon, Seonghae, Shin, Donghoon, Han, HyeKyung, An, Hyungmi, Lee, Jongtae, Lim, Kyoung Soo, Yu, Kyung-Sang, Lee, Howard
Publicado em 2014

Multimodal General Anesthesia: Theory and Practice

Por Brown, Emery N., Pavone, Kara J., Naranjo, Marusa
Publicado no Anesth Analg (2018)

Increasing expression of substance P and calcitonin gene-related peptide in synovial tissue and fluid contribute to the progress of arthritis in developmental dysplasia of the hip

Por Wang, Hui, Zhang, Xiang, He, Ji-Ye, Zheng, Xin-Feng, Li, De, Li, Zheng, Zhu, Jun-Feng, Shen, Chao, Cai, Gui-Quan, Chen, Xiao-Dong
Publicado no Arthritis Res Ther (2015)

High-dose atorvastatin versus moderate dose on early vascular protection after ST-elevation myocardial infarction

Por Gavazzoni, Mara, Gorga, Elio, Derosa, Giuseppe, Maffioli, Pamela, Metra, Marco, Raddino, Riccardo
Publicado no Drug Des Devel Ther (2017)

Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system

Por DeRosa, F, Guild, B, Karve, S, Smith, L, Love, K, Dorkin, J R, Kauffman, K J, Zhang, J, Yahalom, B, Anderson, D G, Heartlein, M W
Publicado no Gene Ther (2016)

Dose-dependent effects of atorvastatin on myocardial infarction

Por Barbarash, Olga, Gruzdeva, Olga, Uchasova, Evgenya, Belik, Ekaterina, Dyleva, Yulia, Karetnikova, Victoria
Publicado no Drug Des Devel Ther (2015)

The combination astemizole–gefitinib as a potential therapy for human lung cancer

Por Chávez-López, María de Guadalupe, Zúñiga-García, Violeta, Hernández-Gallegos, Elisabeth, Vera, Eunice, Chasiquiza-Anchatuña, Carmen Alexandra, Viteri-Yánez, Marco, Sanchez-Ramos, Janet, Garrido, Efraín, Camacho, Javier
Publicado no Onco Targets Ther (2017)

Pharmacokinetic and pharmacodynamic comparison of subcutaneous versus intramuscular leuprolide acetate formulations in male subjects

Por Saltzstein, Daniel, Shore, Neal D., Moul, Judd W., Chu, Franklin, Concepcion, Raoul, de la Motte, Stephan, McLane, John A., Atkinson, Stuart, Yang, Alex, Crawford, E. David
Publicado no Ther Adv Urol (2017)

DKK1 expression by synovial fibroblasts in very early rheumatoid arthritis associates with lymphocyte adhesion in an in vitro flow co-culture system

Por Juarez, Maria, McGettrick, Helen M., Scheel-Toellner, Dagmar, Yeo, Lorraine, Spengler, Julia, de Paz, Banesa, Hardy, Rowan, Cooper, Mark, Raza, Karim, Buckley, Christopher D., Filer, Andrew
Publicado no Arthritis Res Ther (2016)

Dose proportionality and pharmacokinetics of carvedilol sustained-release formulation: a single dose-ascending 10-sequence incomplete block study

Por Kim, Yo Han, Choi, Hee Youn, Noh, Yook-Hwan, Lee, Shi Hyang, Lim, Hyeong-Seok, Kim, Chin, Bae, Kyun-Seop
Publicado no Drug Des Devel Ther (2015)

Effects of Eprosartan on Diastolic Function and Neurohormones in Patients with Hypertension and Diastolic Dysfunction

Por Voors, Adriaan A., van de Wal, Ruud M., L Hartog, Jasper W., Vijn, Richard G., Hummel, Yoran M., Plokker, Thijs W. M., van Veldhuisen, Dirk J., Jaarsma, Wybren
Publicado em 2010

Is increasing the dose of Entecavir effective in partial virological responders?

Por Erturk, Ayse, Adnan Akdogan, Remzi, Parlak, Emine, Cure, Erkan, Cumhur Cure, Medine, Ozturk, Cinar
Publicado em 2014

Analysis of pramipexole dose–response relationships in Parkinson’s disease

Por Wang, Ying, Sun, Sheng-Gang, Zhu, Sui-Qiang, Liu, Chun-Feng, Liu, Yi-Ming, Di, Qing, Shang, Hui-Fang, Ren, Yan, Xiang, Wei, Chen, Sheng-Di
Publicado no Drug Des Devel Ther (2016)

Ameliorative effects of pyrazinoic acid against oxidative and metabolic stress manifested in rats with dimethylhydrazine induced colonic carcinoma

Por Sahdev, Anil K., Raj, Vinit, Singh, Ashok K., Rai, Amit, Keshari, Amit K., De, Arnab, Samanta, Amalesh, Kumar, Umesh, Rawat, Atul, Kumar, Dinesh, Nath, Sneha, Prakash, Anand, Saha, Sudipta
Publicado no Cancer Biol Ther (2017)

Application of physiologically based pharmacokinetic modeling in predicting drug–drug interactions for sarpogrelate hydrochloride in humans

Por Min, Jee Sun, Kim, Doyun, Park, Jung Bae, Heo, Hyunjin, Bae, Soo Hyeon, Seo, Jae Hong, Oh, Euichaul, Bae, Soo Kyung
Publicado no Drug Des Devel Ther (2016)