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Pharmacokinetic and pharmacodynamic comparison of subcutaneous versus intramuscular leuprolide acetate formulations in male subjects

BACKGROUND: The aim of this study was to compare the pharmacokinetics (PK) and pharmacodynamics (PD) of two distinct formulations of leuprolide acetate (LA); subcutaneous (SC) injection and intramuscular (IM) injection. METHODS: A total of 32 healthy men were randomized to receive a single 7.5 mg in...

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Foilsithe in:Ther Adv Urol
Main Authors: Saltzstein, Daniel, Shore, Neal D., Moul, Judd W., Chu, Franklin, Concepcion, Raoul, de la Motte, Stephan, McLane, John A., Atkinson, Stuart, Yang, Alex, Crawford, E. David
Formáid: Artigo
Teanga:Inglês
Foilsithe: SAGE Publications 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805007/
https://ncbi.nlm.nih.gov/pubmed/29434672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756287217738150
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