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4
“From Large-Scale Collections to the Potential Use of Genomic Techniques for Supply of Drug Candidates”
Por David J. Newman
Publicado em 2018-10-01
“...The initial sources of marine-derived compounds that on a small scale exhibited interesting...”
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Natural Products as Sources of New Drugs over the 30 Years from 1981 to 2010()
Por Newman, David J., Cragg, Gordon M.
Publicado em 2012
“... in this journal in 1997, 2003 and 2007. In the case of all approved therapeutic agents, the time frame has been...”
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Inhibitors of SARS-CoV-2 PLpro
“... there are now ∼30 distinct crystal structures with small molecule inhibitors bound in a surprising number...”
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Targeting HCV Entry For Development of Therapeutics
Por Jeffrey F. McKelvy, Flossie Wong-Staal, Andrew J. Syder
Publicado em 2010-08-01
“... the expansion of the infected cell reservoir, and would complement the many replication inhibitors now under...”
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Targeting HCV Entry For Development of Therapeutics
“... the expansion of the infected cell reservoir, and would complement the many replication inhibitors now under...”
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13
Anthracycline-induced cardiotoxicity and the cardiac-sparing effect of liposomal formulation
“... cancer, small cell lung cancer, sarcoma, and breast cancer. Unfortunately, these agents also exhibit a...”
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14
Symbiosis-inspired Approaches to Antibiotic Discovery
“... by the genetic machineries available to the small molecule producer. The human microbiome is now integral...”
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15
The power of sophisticated phenotypic screening and modern mechanism-of-action methods
“.... With the combination of medically inspired phenotypic screening and the development of modern MoA methods, we can now...”
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16
Efficacy of drug prophylaxis.
Por Phillips-Howard, P A
Publicado em 1989
“... drugs, malaria preventive guidelines switched from chloroquine to the newer compound antimalarial drugs...”
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STUDIES UPON CALCAREOUS DEGENERATION : I. THE PROCESS OF PATHOLOGICAL CALCIFICATION.
Por Klotz, Oskar
Publicado em 1905
“... observed in the latter case is that with lowered vitality the cells are unable to utilize the products...”
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