Resultados da pesquisa - ((((drug de) OR (drug dna))v) or (((drug de) OR (drug dna)))) devel ther*

Pesquisas alternativas:
devel ther » novel ther (Expandir a Pesquisa), level theory (Expandir a Pesquisa), develop them (Expandir a Pesquisa)
drug de » drug dose (Expandir a Pesquisa)

61

Virologic breakthrough in a patient with chronic hepatitis B by combination treatment with tenofovir disoproxil fumarate and entecavir

Virologic breakthrough in a patient with chronic hepatitis B by combination treatment with tenofovir disoproxil fumarate and entecavir

Por Suzuki, Fumitaka, Sezaki, Hitomi, Akuta, Norio, Suzuki, Yoshiyuki, Kawamura, Yusuke, Hosaka, Tetsuya, Kobayashi, Masahiro, Saitoh, Satoshi, Arase, Yasuji, Ikeda, Kenji, Kobayashi, Mariko, Watahiki, Sachiyo, Mineta, Rie, Suzuki, Yukiko, Kumada, Hiromitsu
Publicado em 2014

“... monotherapy continuously followed by TDF and ETV combination therapy, because her HBV DNA levels had been >3.5...”
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62

Liriodenine, an aporphine alkaloid from Enicosanthellum pulchrum, inhibits proliferation of human ovarian cancer cells through induction of apoptosis via the mitochondrial signaling pathway and blocking cell cycle progression

Liriodenine, an aporphine alkaloid from Enicosanthellum pulchrum, inhibits proliferation of human ovarian cancer cells through induction of apoptosis via the mitochondrial signalin...

Por Nordin, Noraziah, Majid, Nazia Abdul, Hashim, Najihah Mohd, Rahman, Mashitoh Abd, Hassan, Zalila, Ali, Hapipah Mohd
Publicado no Drug Des Devel Ther (2015)

“.... Initial and late apoptosis was examined by Annexin V-fluorescein isothiocyanate and DNA laddering assays...”
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63

DNAzyme-based probe for circulating microRNA detection in peripheral blood

DNAzyme-based probe for circulating microRNA detection in peripheral blood

Por Shao, Guoli, Ji, Shufeng, Wu, Aiguo, Liu, Cuiping, Wang, Mengchuan, Zhang, Pusheng, Jiao, Qingli, Kang, Yuzhan
Publicado no Drug Des Devel Ther (2015)

“... amplification. METHODS: The miRNA probes were chemically synthesized with a phosphate at the 5′ end and purified...”
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64

Sensitization of gastric cancer cells to alkylating agents by glaucocalyxin B via cell cycle arrest and enhanced cell death

Sensitization of gastric cancer cells to alkylating agents by glaucocalyxin B via cell cycle arrest and enhanced cell death

Por Ur Rahman, Muhammad Saif, Zhang, Ling, Wu, Lingyan, Xie, Yuqiong, Li, Chunchun, Cao, Jiang
Publicado no Drug Des Devel Ther (2017)

“... can be reduced by using sensitizing agents in combination with therapeutic drugs. In this study...”
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65

High-dose dexamethasone induced LPS-stimulated rat alveolar macrophages apoptosis

High-dose dexamethasone induced LPS-stimulated rat alveolar macrophages apoptosis

Por Zeng, Si, Qiao, Hui, Lv, Xue-wen, Fan, Dan, Liu, Tong, Xie, Dongli
Publicado no Drug Des Devel Ther (2017)

“... in vitro. Transmission electron microscopy and DNA fragmentation analysis demonstrated that 10(−4) and 10...”
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66

Isolation and evaluation of biological efficacy of quercetol in human hepatic carcinoma cells

Isolation and evaluation of biological efficacy of quercetol in human hepatic carcinoma cells

Por Ali, Huma, Dixit, Savita, Ali, Daoud, Alkahtane, Abdullah A, Alarifi, Saud, Ali, Bahy A, Alkahtani, Saad
Publicado no Drug Des Devel Ther (2016)

“... tests and comet assay for genotoxicity, using HepG2 cells, over 24 hours. Data from 3-(4,5...”
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67

In vivo study of doxorubicin-loaded cell-penetrating peptide-modified pH-sensitive liposomes: biocompatibility, bio-distribution, and pharmacodynamics in BALB/c nude mice bearing human breast tumors

In vivo study of doxorubicin-loaded cell-penetrating peptide-modified pH-sensitive liposomes: biocompatibility, bio-distribution, and pharmacodynamics in BALB/c nude mice bearing h...

Por Ding, Yuan, Cui, Wei, Sun, Dan, Wang, Gui-Ling, Hei, Yu, Meng, Shuai, Chen, Jian-Hua, Xie, Ying, Wang, Zhi-Qiang
Publicado no Drug Des Devel Ther (2017)

“...In vivo evaluation of drug delivery vectors is essential for clinical translation. In BALB/c nude...”
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68

Oxidative stress-induced cell cycle blockage and a protease-independent programmed cell death in microaerophilic Giardia lamblia

Oxidative stress-induced cell cycle blockage and a protease-independent programmed cell death in microaerophilic Giardia lamblia

Por Ghosh, Esha, Ghosh, Arjun, Ghosh, Amar Nath, Nozaki, Tomoyoshi, Ganguly, Sandipan
Publicado em 2009

“... AnnexinV-FITC assay, DNA fragmentation pattern, etc. On the contrary, Caspase-9 assay, which confirms...”
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69

Update on the clinical utility of once-daily tacrolimus in the management of transplantation

Update on the clinical utility of once-daily tacrolimus in the management of transplantation

Por Posadas Salas, Maria Aurora, Srinivas, Titte R
Publicado em 2014

“...Adherence to immunosuppression and minimizing variability in drug exposure are important...”
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70

Targeted inhibition of mammalian target of rapamycin (mTOR) enhances radiosensitivity in pancreatic carcinoma cells

Targeted inhibition of mammalian target of rapamycin (mTOR) enhances radiosensitivity in pancreatic carcinoma cells

Por Dai, Zhi-Jun, Gao, Jie, Kang, Hua-Feng, Ma, Yu-Guang, Ma, Xiao-Bin, Lu, Wang-Feng, Lin, Shuai, Ma, Hong-Bing, Wang, Xi-Jing, Wu, Wen-Ying
Publicado em 2013

“... showing that RPM sensitizes cancers to chemotherapy and radiation therapy have attracted considerable...”
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71

Baracle(®) vs Baraclude(®) for 48 weeks in patients with treatment-naïve chronic hepatitis B: a comparison of efficacy and safety

Baracle(®) vs Baraclude(®) for 48 weeks in patients with treatment-naïve chronic hepatitis B: a comparison of efficacy and safety

Por Kim, Do Young, Kim, Ju Hyun, Tak, Won Young, Yeon, Jong Eun, Lee, Joon Hyeok, Yoon, Jung Hwan, Lee, Youn Jae, Lee, Byung Seok, Han, Byung Hoon, Lee, Han Chu
Publicado no Drug Des Devel Ther (2017)

“..., comparative trial, 118 treatment-naïve patients with CHB were randomly assigned to receive either 0.5 mg...”
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72

Sildenafil potentiates the antitumor activity of cisplatin by induction of apoptosis and inhibition of proliferation and angiogenesis

Sildenafil potentiates the antitumor activity of cisplatin by induction of apoptosis and inhibition of proliferation and angiogenesis

Por El-Naa, Mona Mohamed, Othman, Mohamed, Younes, Sheren
Publicado no Drug Des Devel Ther (2016)

“...Sildenafil is the first phosphodiesterase-5 inhibitor used for the treatment of erectile...”
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73

Mechanisms underlying probucol-induced hERG-channel deficiency

Mechanisms underlying probucol-induced hERG-channel deficiency

Por Shi, Yuan-Qi, Yan, Cai-Chuan, Zhang, Xiao, Yan, Meng, Liu, Li-Rong, Geng, Huai-Ze, Lv, Lin, Li, Bao-Xin
Publicado no Drug Des Devel Ther (2015)

“... arrhythmias (torsades de pointes) or sudden death. Probucol is a cholesterol-lowering drug that could reduce...”
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74

Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung cancer

Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung c...

Por Ren, Tao, Shan, Jinlu, Li, Mengxia, Qing, Yi, Qian, Chengyuan, Wang, Guangjie, Li, Qing, Lu, Guoshou, Li, Chongyi, Peng, Yu, Luo, Hao, Zhang, Shiheng, Yang, Yuxing, Cheng, Yi, Wang, Dong, Zhou, Shu-Feng
Publicado no Drug Des Devel Ther (2015)

“... the proapoptotic activity of CDDP in A549 cells. AT-101 also enhanced the inhibitory effect of CDDP on DNA repair...”
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75

Ursolic acid sensitizes cisplatin-resistant HepG2/DDP cells to cisplatin via inhibiting Nrf2/ARE pathway

Ursolic acid sensitizes cisplatin-resistant HepG2/DDP cells to cisplatin via inhibiting Nrf2/ARE pathway

Por Wu, Shouhai, Zhang, Tianpeng, Du, Jingsheng
Publicado no Drug Des Devel Ther (2016)

“...BACKGROUND: Combinations of adjuvant sensitizers with anticancer drugs is a promising new strategy...”
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76

Isolation and evaluation of anticancer efficacy of stigmasterol in a mouse model of DMBA-induced skin carcinoma

Isolation and evaluation of anticancer efficacy of stigmasterol in a mouse model of DMBA-induced skin carcinoma

Por Ali, Huma, Dixit, Savita, Ali, Daoud, Alqahtani, Saeed M, Alkahtani, Saad, Alarifi, Saud
Publicado no Drug Des Devel Ther (2015)

“... dismutase, and catalase as compared with the control. Elevated levels of lipid peroxide and DNA damage...”
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77

Antimutagenic and antioxidant activity of novel 4-substituted phenyl-2,2′-bichalcophenes and aza-analogs

Antimutagenic and antioxidant activity of novel 4-substituted phenyl-2,2′-bichalcophenes and aza-analogs

Por El-Sayed, Wael M, Hussin, Warda A
Publicado em 2013

“... of great interest for the development of novel therapeutics for many diseases including cancer. Ten novel...”
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78

Influence of caffeine and hyaluronic acid on collagen biosynthesis in human skin fibroblasts

Influence of caffeine and hyaluronic acid on collagen biosynthesis in human skin fibroblasts

Por Donejko, Magdalena, Przylipiak, Andrzej, Rysiak, Edyta, Głuszuk, Katarzyna, Surażyński, Arkadiusz
Publicado em 2014

“... fibroblast cultures that had been treated with 1, 2, and 5 mM caffeine and with caffeine and 500 μg/mL HA...”
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79

Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1

Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1

Por Sui, Jiangdong, Li, Mengxia, Qian, Chengyuan, Wang, Shufeng, Cheng, Yi, Chen, Benjamin PC, Wang, Dong
Publicado no Drug Des Devel Ther (2014)

“... possessing both DNA repair and redox regulatory activities. It has been shown that blocking redox function...”
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80

Flavokawain derivative FLS induced G2/M arrest and apoptosis on breast cancer MCF-7 cell line

Flavokawain derivative FLS induced G2/M arrest and apoptosis on breast cancer MCF-7 cell line

Por Ali, Norlaily Mohd, Akhtar, M Nadeem, Ky, Huynh, Lim, Kian Lam, Abu, Nadiah, Zareen, Seema, Ho, Wan Yong, Alan-Ong, Han Kiat, Tan, Sheau Wei, Alitheen, Noorjahan Banu, Ismail, Jamil bin, Yeap, Swee Keong, Kamarul, Tunku
Publicado no Drug Des Devel Ther (2016)

“... potential therapeutic value for flavokawain derivative FLS to be further developed as a new anticancer drug....”
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