Resultados da pesquisa - (((( j al como can now ) OR ( j data complex trait non ))) OR ( 3 coil clamp can netw ))

1

Quantifying Selection Acting on a Complex Trait Using Allele Frequency Time Series Data

Por Illingworth, Christopher J.R., Parts, Leopold, Schiffels, Stephan, Liti, Gianni, Mustonen, Ville
Publicado em 2012

“..., Cubillos FA, Warringer J, et al. [14 co-authors]. 2011. Revealing the genetic structure of a trait...”
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Assessing the Heritability of Complex Traits in Humans: Methodological Challenges and Opportunities

Por Mayhew, Alexandra J., Meyre, David
Publicado no Curr Genomics (2017)

“... estimates for complex traits such as obesity are determined and to explore the future directions of research...”
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Predicting complex traits using a diffusion kernel on genetic markers with an application to dairy cattle and wheat data

Por Morota, Gota, Koyama, Masanori, M Rosa, Guilherme J, Weigel, Kent A, Gianola, Daniel
Publicado em 2013

“... developed to model discrete marker inputs, using Holstein cattle and wheat data. This kernel can be viewed...”
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A novel iterative mixed model to remap three complex orthopedic traits in dogs

Por Huang, Meng, Hayward, Jessica J., Corey, Elizabeth, Garrison, Susan J., Wagner, Gabriela R., Krotscheck, Ursula, Hayashi, Kei, Schweitzer, Peter A., Lust, George, Boyko, Adam R., Todhunter, Rory J.
Publicado no PLoS One (2017)

“... (RCCL) are the most common complex orthopedic traits of dogs and all result in debilitating...”
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Pharmacogenomic variants have larger effect sizes than genetic variants associated with other dichotomous complex traits

Por Maranville, Joseph C., Cox, Nancy J.
Publicado no Pharmacogenomics J (2015)

“... with larger effect sizes than other phenotypes, such as complex disease risk. This is presumed to reflect...”
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Leveraging genetically simple traits to identify small-effect variants for complex phenotypes

Por Kemper, K. E., Littlejohn, M. D., Lopdell, T., Hayes, B. J., Bennett, L. E., Williams, R. P., Xu, X. Q., Visscher, P. M., Carrick, M. J., Goddard, M. E.
Publicado no BMC Genomics (2016)

“... demonstrate this approach in a dairy cattle data set where the complex traits were milk production phenotypes...”
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Joint prediction of multiple quantitative traits using a Bayesian multivariate antedependence model

Por Jiang, J, Zhang, Q, Ma, L, Li, J, Wang, Z, Liu, J-F
Publicado no Heredity (Edinb) (2015)

“... traditional counterparts (Bayes A and multi-trait Bayes A) under various scenarios. Our method can be readily...”
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Putative enhancer sites in the bovine genome are enriched with variants affecting complex traits

Por Wang, Min, Hancock, Timothy P., MacLeod, Iona M., Pryce, Jennie E., Cocks, Benjamin G., Hayes, Benjamin J.
Publicado no Genet Sel Evol (2017)

“... to the variation in complex traits. The level of enrichment was higher in bovine-specific enhancer regions...”
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A Hierarchical Bayesian Approach to Multi-Trait Clinical Quantitative Trait Locus Modeling

Por Mutshinda, Crispin M., Noykova, Neli, Sillanpää, Mikko J.
Publicado em 2012

“... advocated as an effective approach to dissecting the genetic architecture of complex phenotypic traits...”
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Multiple loci are linked with anti-red blood cell antibody production in NZB mice – comparison with other phenotypes implies complex modes of action

Por LEE, N J, RIGBY, R J, GILL, H, BOYLE, J J, FOSSATI-JIMACK, L, MORLEY, B J, VYSE, T J
Publicado em 2004

“... of NZB origin, and three derived from the non-autoimmune BALB/c background. A comparison between loci...”
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Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4)

Por Strug, Lisa J, Clarke, Tara, Chiang, Theodore, Chien, Minchen, Baskurt, Zeynep, Li, Weili, Dorfman, Ruslan, Bali, Bhavna, Wirrell, Elaine, Kugler, Steven L, Mandelbaum, David E, Wolf, Steven M, McGoldrick, Patricia, Hardison, Huntley, Novotny, Edward J, Ju, Jingyue, Greenberg, David A, Russo, James J, Pal, Deb K
Publicado em 2009

“... in Elongator Protein Complex 4 (ELP4) in two independent data sets; the strongest evidence was with rs986527...”
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Influence of H-2 and non-H-2 genes on resistance to murine cytomegalovirus infection.

Por Grundy, J E, Mackenzie, J S, Stanley, N F
Publicado em 1981

“... by genes linked to the H-2 complex. The k haplotype is approximately 10 times more resistant than the b...”
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Invited Commentary: Gene × Lifestyle Interactions and Complex Disease Traits—Inferring Cause and Effect From Observational Data, Sine Qua Non

Por Franks, Paul W., Nettleton, Jennifer A.
Publicado em 2010

“... of relations between lifestyle factors and common complex diseases such as type 2 diabetes. Recent major...”
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The Brisbane Systems Genetics Study: Genetical Genomics Meets Complex Trait Genetics

Por Powell, Joseph E., Henders, Anjali K., McRae, Allan F., Caracella, Anthony, Smith, Sara, Wright, Margaret J., Whitfield, John B., Dermitzakis, Emmanouil T., Martin, Nicholas G., Visscher, Peter M., Montgomery, Grant W.
Publicado em 2012

“... changes of gene regulation acting in complex pathways. Clearly understanding the molecular genetic...”
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Constructing Endophenotypes of Complex Diseases Using Non-Negative Matrix Factorization and Adjusted Rand Index

Por Wang, Hui-Min, Hsiao, Ching-Lin, Hsieh, Ai-Ru, Lin, Ying-Chao, Fann, Cathy S. J.
Publicado em 2012

“..., offer a simplified approach to dissect complex trait by reducing genetic heterogeneity. Because...”
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A family-based joint test for mean and variance heterogeneity for quantitative traits

Por CAO, YING, MAXWELL, TAYLOR J., WEI, PENG
Publicado no Ann Hum Genet (2014)

“... heterogeneity (vQTL), which is important in studying genetic association with complex traits, especially...”
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Identifying disease sensitive and quantitative trait-relevant biomarkers from multidimensional...

Por Wang, Hua, Nie, Feiping, Huang, Heng, Risacher, Shannon L., Saykin, Andrew J., Shen, Li
Publicado em 2012

“... sparse multimodal multitask learning method to reveal complex relationships from gene to brain to symptom...”
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A Framework for Interpreting Type I Error Rates from a Product‐Term Model of Interaction Applied to Quantitative Traits

Por Rao, Tara J., Province, Michael A.
Publicado no Genet Epidemiol (2015)

“... for interactive effects on complex traits. After observing unexpected variability in type I error rates from SNP...”
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GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network

Por Bahram Namjou, Todd Lingren, Yongbo Huang, Sreeja Parameswaran, Beth L. Cobb, Ian B. Stanaway, John J. Connolly, Frank D. Mentch, Barbara Benoit, Xinnan Niu, Wei-Qi Wei, Robert J. Carroll, Jennifer A. Pacheco, Isaac T. W. Harley, Senad Divanovic, David S. Carrell, Eric B. Larson, David J. Carey, Shefali Verma, Marylyn D. Ritchie, Ali G. Gharavi, Shawn Murphy, Marc S. Williams, David R. Crosslin, Gail P. Jarvik, Iftikhar J. Kullo, Hakon Hakonarson, Rongling Li, The eMERGE Network, Stavra A. Xanthakos, John B. Harley
Publicado em 2019-07-01

“... in participants with European ancestry. At the PNPLA3-SAMM50 region, three SNPs, rs738409, rs738408, and rs3747207...”
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Application of a Bayesian non-linear model hybrid scheme to sequence data for genomic prediction and QTL mapping

Por Wang, Tingting, Chen, Yi-Ping Phoebe, MacLeod, Iona M., Pryce, Jennie E., Goddard, Michael E., Hayes, Ben J.
Publicado no BMC Genomics (2017)

“... complex traits. For some traits, the most accurate genomic predictions are achieved with non-linear...”
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