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Quantifying Selection Acting on a Complex Trait Using Allele Frequency Time Series Data

When selection is acting on a large genetically diverse population, beneficial alleles increase in frequency. This fact can be used to map quantitative trait loci by sequencing the pooled DNA from the population at consecutive time points and observing allele frequency changes. Here, we present a po...

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Détails bibliographiques
Auteurs principaux: Illingworth, Christopher J.R., Parts, Leopold, Schiffels, Stephan, Liti, Gianni, Mustonen, Ville
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731369/
https://ncbi.nlm.nih.gov/pubmed/22114362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msr289
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