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Quantifying Selection Acting on a Complex Trait Using Allele Frequency Time Series Data

When selection is acting on a large genetically diverse population, beneficial alleles increase in frequency. This fact can be used to map quantitative trait loci by sequencing the pooled DNA from the population at consecutive time points and observing allele frequency changes. Here, we present a po...

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Detalhes bibliográficos
Main Authors: Illingworth, Christopher J.R., Parts, Leopold, Schiffels, Stephan, Liti, Gianni, Mustonen, Ville
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731369/
https://ncbi.nlm.nih.gov/pubmed/22114362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msr289
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