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Quantifying Selection Acting on a Complex Trait Using Allele Frequency Time Series Data

When selection is acting on a large genetically diverse population, beneficial alleles increase in frequency. This fact can be used to map quantitative trait loci by sequencing the pooled DNA from the population at consecutive time points and observing allele frequency changes. Here, we present a po...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Illingworth, Christopher J.R., Parts, Leopold, Schiffels, Stephan, Liti, Gianni, Mustonen, Ville
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731369/
https://ncbi.nlm.nih.gov/pubmed/22114362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msr289
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