Metformin modulates mitochondrial function and mitophagy in peripheral blood mononuclear cells from type 2 diabetic patients

Por Aranzazu M. de Marañón, Pedro Díaz-Pozo, Francisco Canet, Noelia Díaz-Morales, Zaida Abad-Jiménez, Sandra López-Domènech, Teresa Vezza, Nadezda Apostolova, Carlos Morillas, Milagros Rocha, Víctor M. Víctor
Publicado em 2022-07-01

An increase in surface hydrophobicity mediates chaperone activity in N-chlorinated RidA

Por Marharyta Varatnitskaya, Julia Fasel, Alexandra Müller, Natalie Lupilov, Yunlong Shi, Kristin Fuchs, Marco Krewing, Christoph Jung, Timo Jacob, Barbara Sitek, Julia E. Bandow, Kate S. Carroll, Eckhard Hofmann, Lars I. Leichert
Publicado em 2022-07-01

Mitochondrial thioredoxin system is required for enhanced stress resistance and extended longevity in long-lived mitochondrial mutants

Por Namastheé Harris-Gauthier, Annika Traa, Abdelrahman AlOkda, Alibek Moldakozhayev, Ulrich Anglas, Sonja K. Soo, Jeremy M. Van Raamsdonk
Publicado em 2022-07-01

HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage-independence

Por Yeon Soo Kim, Priscilla W. Tang, Jaclyn E. Welles, Weihua Pan, Zaineb Javed, Amal Taher Elhaw, Karthikeyan Mythreye, Scot R. Kimball, Nadine Hempel
Publicado em 2022-07-01

Cellular redox imbalance on the crossroad between mitochondrial dysfunction, senescence, and proliferation

Por Rumiana Bakalova, Ichio Aoki, Zhivko Zhelev, Tatsuya Higashi
Publicado em 2022-07-01

TIGAR alleviates oxidative stress in brain with extended ischemia via a pentose phosphate pathway-independent manner

Por Mengru Liu, Xinyu Zhou, Yue Li, Shijia Ma, Ling Pan, Xingxian Zhang, Wanqing Zheng, Zhanxun Wu, Ke Wang, Anil Ahsan, Jiaying Wu, Lei Jiang, Yangyang Lu, Weiwei Hu, Zhenghong Qin, Zhong Chen, Xiangnan Zhang
Publicado em 2022-07-01

AKAP12 ameliorates liver injury via targeting PI3K/AKT/PCSK6 pathway

Por Xuan Wu, Yuhong Luo, Shan Wang, Yueying Li, Meiyu Bao, Yuanjiang Shang, Lei Chen, Weiwei Liu
Publicado em 2022-07-01

BAP1 phosphorylation-mediated Sp1 stabilization plays a critical role in cathepsin K inhibition-induced C-terminal p53-dependent Bax upregulation

Por Seung Un Seo, Seon Min Woo, Seul Gi Lee, Min Yeong Kim, Hyun Shik Lee, Yung Hyun Choi, Sang Hyun Kim, Young-Chae Chang, Kyoung-jin Min, Taeg Kyu Kwon
Publicado em 2022-07-01

Maternal heme-enriched diet promotes a gut pro-oxidative status associated with microbiota alteration, gut leakiness and glucose intolerance in mice offspring

Por Anaïs Mazenc, Loïc Mervant, Claire Maslo, Corinne Lencina, Valérie Bézirard, Mathilde Levêque, Ingrid Ahn, Valérie Alquier-Bacquié, Nathalie Naud, Cécile Héliès-Toussaint, Laurent Debrauwer, Sylvie Chevolleau, Françoise Guéraud, Fabrice H.F. Pierre, Vassilia Théodorou, Maïwenn Olier
Publicado em 2022-07-01

Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells

Por Gilles Rademaker, Yasmine Boumahd, Raphaël Peiffer, Sandy Anania, Tom Wissocq, Maude Liégeois, Géraldine Luis, Nor Eddine Sounni, Ferman Agirman, Naïma Maloujahmoum, Pascal De Tullio, Marc Thiry, Akeila Bellahcène, Vincent Castronovo, Olivier Peulen
Publicado em 2022-07-01

Mfn2-mediated mitochondrial fusion alleviates doxorubicin-induced cardiotoxicity with enhancing its anticancer activity through metabolic switch

Por Mingge Ding, Rui Shi, Shuli Cheng, Man Li, Dema De, Chaoyang Liu, Xiaoming Gu, Juan Li, Shumiao Zhang, Min Jia, Rong Fan, Jianming Pei, Feng Fu
Publicado em 2022-06-01

Hypoxia-induced HIF-1α/lncRNA-PMAN inhibits ferroptosis by promoting the cytoplasmic translocation of ELAVL1 in peritoneal dissemination from gastric cancer

Por Zaihuan Lin, Jialin Song, Yuke Gao, Sihao Huang, Rongzhang Dou, Panyi Zhong, Guoquan Huang, Lei Han, Jinsen Zheng, Xinyao Zhang, Shuyi Wang, Bin Xiong
Publicado em 2022-06-01

Mechano-signaling via Piezo1 prevents activation and p53-mediated senescence of muscle stem cells

Por Yundong Peng, Jingjing Du, Stefan Günther, Xinyue Guo, Shengpeng Wang, Andre Schneider, Li Zhu, Thomas Braun
Publicado em 2022-06-01

Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study

Por Marta Galvez-Fernandez, Francisco Sanchez-Saez, Arce Domingo-Relloso, Zulema Rodriguez-Hernandez, Sonia Tarazona, Vannina Gonzalez-Marrachelli, Maria Grau-Perez, Jose M. Morales-Tatay, Nuria Amigo, Tamara Garcia-Barrera, Jose L. Gomez-Ariza, F. Javier Chaves, Ana Barbara Garcia-Garcia, Rebeca Melero, Maria Tellez-Plaza, Juan C. Martin-Escudero, Josep Redon, Daniel Monleon
Publicado em 2022-06-01

Architecture of the NADPH oxidase family of enzymes

Por Blessing C. Ogboo, Uriy V. Grabovyy, Aniket Maini, Scott Scouten, Albert van der Vliet, Andrea Mattevi, David E. Heppner
Publicado em 2022-06-01

Reactive oxygen species in the world ocean and their impacts on marine ecosystems

Por J. Jeffrey Morris, Andrew L. Rose, Zhiying Lu
Publicado em 2022-06-01

Corrigendum to “Mfn2-mediated mitochondrial fusion alleviates doxorubicin-induced cardiotoxicity with enhancing its anticancer activity through metabolic switch” [Redox Biol. 52 (2...

Por Mingge Ding, Rui Shi, Shuli Cheng, Man Li, Dema De, Chaoyang Liu, Xiaoming Gu, Juan Li, Shumiao Zhang, Min Jia, Rong Fan, Jianming Pei, Feng Fu
Publicado em 2022-06-01

Overexpression of NAG-1/GDF15 prevents hepatic steatosis through inhibiting oxidative stress-mediated dsDNA release and AIM2 inflammasome activation

Por Ying Wang, Chaojie Chen, Jiajun Chen, Tingting Sang, He Peng, Xiaojian Lin, Qian Zhao, Shengjia Chen, Thomas Eling, Xingya Wang
Publicado em 2022-06-01

Dietary salt initiates redox signaling between endothelium and vascular smooth muscle through NADPH oxidase 4

Por Kai er Ying, Wenguang Feng, Wei-Zhong Ying, Xingsheng Li, Dongqi Xing, Yong Sun, Yabing Chen, Paul W. Sanders
Publicado em 2022-06-01

Fatty acids derived from apoptotic chondrocytes fuel macrophages FAO through MSR1 for facilitating BMSCs osteogenic differentiation

Por Zi-Yang Zheng, Tao Jiang, Zhen-Fei Huang, Bo Chu, Jun Gu, Xuan Zhao, Hao Liu, Jin Fan, Li-Peng Yu, Shu-Heng Jiang, Qing Li, Li-Peng Hu, Fan-Qi Kong, Lai Zhang, Qi Chen, Jian Chen, Han-Wen Zhang, Guo-Yong Yin, Shu-Jie Zhao
Publicado em 2022-07-01