Alpha-glucosidase and Alpha-amylase Inhibitors Derived from Naturally Occurring Prenylated Isoflavones

A series of prenylated isoflavones were synthesized to evaluate their inhibitory effect against α-glucosidase and α-amylase enzymes, analyzing the bioisosteric effect of the linear or cyclized prenyl moiety in these benzopyran derivatives. Compound 5a exhibited higher α-glucosidase inhibition (IC50...

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发表在:	Journal of the Mexican Chemical Society
Principais autores:	Brandon Hernández-Gutiérrez, María C. Cruz-López, Omar Gómez-García, Elvia Becerra-Martínez, Fabiola E. Jiménez-Montejo, Aarón Mendieta-Moctezuma
格式:	Artigo
语言:	Inglês
出版:	Sociedad Química de México 2024
主题:	Multidisciplinaria (Ciencias Naturales y Exactas)
在线阅读:	https://www.redalyc.org/articulo.oa?id=47581848012 https://www.redalyc.org/journal/475/47581848012/ https://www.redalyc.org/journal/475/47581848012/html/ https://www.redalyc.org/journal/475/47581848012/47581848012.epub https://www.redalyc.org/journal/475/47581848012/movil
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