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Alpha-glucosidase and Alpha-amylase Inhibitors Derived from Naturally Occurring Prenylated Isoflavones

A series of prenylated isoflavones were synthesized to evaluate their inhibitory effect against α-glucosidase and α-amylase enzymes, analyzing the bioisosteric effect of the linear or cyclized prenyl moiety in these benzopyran derivatives. Compound 5a exhibited higher α-glucosidase inhibition (IC50...

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Vydáno v:Journal of the Mexican Chemical Society
Hlavní autoři: Brandon Hernández-Gutiérrez, María C. Cruz-López, Omar Gómez-García, Elvia Becerra-Martínez, Fabiola E. Jiménez-Montejo, Aarón Mendieta-Moctezuma
Médium: Artigo
Jazyk:Inglês
Vydáno: Sociedad Química de México 2024
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On-line přístup:https://www.redalyc.org/articulo.oa?id=47581848012
https://www.redalyc.org/journal/475/47581848012/
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https://www.redalyc.org/journal/475/47581848012/47581848012.epub
https://www.redalyc.org/journal/475/47581848012/movil
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