In silico, Synthesis and Biological Investigations of Pyrrolo[3,4- C]Pyrrole Hydroxamic Acid Derivatives as Potential Anticancer Agents

Based in a general structural pharmacophore model of suberoylanilide hydroxamic acid (commercially known as Vorinostat©), we synthesized a series of new pyrrolo[3,4- c ]pyrrole hydroxamic acid derivatives, 9a-c, to be tested as candidates for anti-cancer drugs . The evaluation of their poss...

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में प्रकाशित:	Journal of the Mexican Chemical Society
मुख्य लेखकों:	Luis Bahena, Carlos Cervantes, Karla J Soto-Arredondo, Minerva Martínez-Alfaro, Natanael Zarco, Marco A. García-Revilla, Yolanda Alcaraz-Contreras, Lourdes Palma Tirado, Miguel A. Vázquez, Juvencio Robles
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Sociedad Química de México 2017
विषय:	Multidisciplinaria (Ciencias Naturales y Exactas)
ऑनलाइन पहुंच:	https://www.redalyc.org/articulo.oa?id=47554335004
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