Synthesis of 2,4-Disubstituted Thiazole Combinatorial Unit on Solid-Phase: Microwave Assisted Conversion of Alcohol to Amine Monitored by FT-IR

Microwave-assisted solid-phase synthesis of the 2,4-disubstituted thiazole 3 on Merrifield Resinis described. The hydroxyl moiety was converted to amine in five steps – including coupling andcleavage – within a total reaction time of 2 hours and 26% overall yield. The entire solid-phase synthesiswas...

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發表在:	Journal of the Mexican Chemical Society
Principais autores:	Dyeison Antonow, S. Graciela Mahler, Gloria L. Serra, Eduardo Manta, Vera Lucia Eifler Lima
格式:	Artigo
語言:	Inglês
出版:	Sociedad Química de México 2005
主題:	Multidisciplinaria (Ciencias Naturales y Exactas)
在線閱讀:	https://www.redalyc.org/articulo.oa?id=47549223
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