Synthesis of 2,4-Disubstituted Thiazole Combinatorial Unit on Solid-Phase: Microwave Assisted Conversion of Alcohol to Amine Monitored by FT-IR
Microwave-assisted solid-phase synthesis of the 2,4-disubstituted thiazole 3 on Merrifield Resinis described. The hydroxyl moiety was converted to amine in five steps including coupling andcleavage within a total reaction time of 2 hours and 26% overall yield. The entire solid-phase synthesiswas...
Spremljeno u:
| Izdano u: | Journal of the Mexican Chemical Society |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Sociedad Química de México
2005
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| Teme: | |
| Online pristup: | https://www.redalyc.org/articulo.oa?id=47549223 |
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