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Synthesis of potential anti-inflammatory compounds, selective inhibitors of cyclooxygenase-2 (COX-2)

Seven compounds were synthesized as potential antiinflammatorydrugs, selective inhibitors of the enzyme cyclooxygenase-2 (COX-2). The structural design was based on the knowledgeof the active site of the enzyme. The synthesized compounds presenta combined naproxen and celecoxib structures.

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Foilsithe in:Journal of the Mexican Chemical Society
Main Authors: Blanca E. Trejo, Francisco J. López Muñoz, Angel Guzmán, Eduardo Díaz
Formáid: Artigo
Teanga:Inglês
Foilsithe: Sociedad Química de México 2004
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Rochtain Ar Líne:https://www.redalyc.org/articulo.oa?id=47548404
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