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Synthesis of potential anti-inflammatory compounds, selective inhibitors of cyclooxygenase-2 (COX-2)
Seven compounds were synthesized as potential antiinflammatorydrugs, selective inhibitors of the enzyme cyclooxygenase-2 (COX-2). The structural design was based on the knowledgeof the active site of the enzyme. The synthesized compounds presenta combined naproxen and celecoxib structures.
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| Publicado en: | Journal of the Mexican Chemical Society |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Sociedad Química de México
2004
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| Materias: | |
| Acceso en línea: | https://www.redalyc.org/articulo.oa?id=47548404 |
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