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Enantioselective Ring Opening of meso-Cyclohexene Epoxide with Phenyllithium Catalyzed by Chiral Schiff Base Ligands

A library of chiral Schiff base ligands was synthesizedfrom aromatic aldehydes and chiral amino alcohols. These ligandswere then screened as catalysts in the asymmetric ring opening ofmeso-cyclohexene epoxide with phenyllithium to give (1S,2R)-phenylcyclohexanol in 9-67% ee.

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Publicat a:Journal of the Mexican Chemical Society
Autors principals: Norma Aidé Cortez, Lars H. Hellberg, Lucía Z. Flores López, Ratnasamy Somanathan, Miguel Parra Hake, Gerardo Aguirre
Format: Artigo
Idioma:Inglês
Publicat: Sociedad Química de México 2004
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Accés en línia:https://www.redalyc.org/articulo.oa?id=47548111
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