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Synthesis and Properties of 2-diazo-1-[2-(thiophen-2-ylmethoxy)- phenyl]-ethanone. Intramolecular Cyclization Through a Carbenoid Intermediate

The synthesis of 2-diazo-1-[2-(thiophen-2-ylmethoxy)-phenyl]-ethanone (1) is described. The procedure involves an aromaticnucleophilic substitution between the sodium 2-thiophenylmethoxide and 2-fluorobenzaldehyde, the subsequent mild-conditionoxidation to the corresponding carboxylic acid, and fina...

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Publicat a:Journal of the Mexican Chemical Society
Autors principals: Abraham Arceo de la, Erick Cuevas, Raymundo Cruz, Joseph M. Muchowski
Format: Artigo
Idioma:Inglês
Publicat: Sociedad Química de México 2003
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Accés en línia:https://www.redalyc.org/articulo.oa?id=47547221
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