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Inhibition of Phosphofructokinase by Molluscicidal Sesquiterpene Lactones

The effect of ten molluscicidal sesquiterpene lactones wastested on the enzyme phosphofructokinase (PKF) from rabbit muscle.PFK was inhibited irreversibly by all the sesquiterpene lactones tested.7a-Hydroxy-3-desoxyzaluzanin C (2) exhibited the highest efficacyof inhibition with a Ki value of 90 nM....

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Bibliografische gegevens
Gepubliceerd in:Journal of the Mexican Chemical Society
Hoofdauteurs: David Vargas, Ezzat S. Younathan, Nikolaus H. Fischer
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Sociedad Química de México 2001
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Online toegang:https://www.redalyc.org/articulo.oa?id=47545405
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