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Inhibition of Phosphofructokinase by Molluscicidal Sesquiterpene Lactones

The effect of ten molluscicidal sesquiterpene lactones wastested on the enzyme phosphofructokinase (PKF) from rabbit muscle.PFK was inhibited irreversibly by all the sesquiterpene lactones tested.7a-Hydroxy-3-desoxyzaluzanin C (2) exhibited the highest efficacyof inhibition with a Ki value of 90 nM....

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Pubblicato in:Journal of the Mexican Chemical Society
Autori principali: David Vargas, Ezzat S. Younathan, Nikolaus H. Fischer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Sociedad Química de México 2001
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Accesso online:https://www.redalyc.org/articulo.oa?id=47545405
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