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Inhibition of Phosphofructokinase by Molluscicidal Sesquiterpene Lactones

The effect of ten molluscicidal sesquiterpene lactones wastested on the enzyme phosphofructokinase (PKF) from rabbit muscle.PFK was inhibited irreversibly by all the sesquiterpene lactones tested.7a-Hydroxy-3-desoxyzaluzanin C (2) exhibited the highest efficacyof inhibition with a Ki value of 90 nM....

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Publicado no:Journal of the Mexican Chemical Society
Main Authors: David Vargas, Ezzat S. Younathan, Nikolaus H. Fischer
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedad Química de México 2001
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Acesso em linha:https://www.redalyc.org/articulo.oa?id=47545405
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