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Synthesis of Some Novel Derivatives of 2-(9H-purin-6-ylsulfanyl) Acetohydrazide as Potential Antithyroid Agents

Some novel derivatives of 2-(9H-Purin-6-ylsulfanyl)acetohydrazide were synthesized by reacting it with respective aldehydes in ethanol. The antithyroid effect of these compounds was ascertained in vitro by studying their complexation with iodine spectrophotometrically. In vivo, the hormonal as well...

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Bibliographic Details
Published in:Journal of the Mexican Chemical Society
Main Authors: Ismat Fatima, Munawar A. Munawar, Waqar Nasir, Misbahul A. Khan, Affia Tasneem, Tauqir Fatima, Muhammad R. Adil
Format: Artigo
Language:Inglês
Published: Sociedad Química de México 2012
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Online Access:https://www.redalyc.org/articulo.oa?id=47525153002
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