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Synthesis of Some Novel Derivatives of 2-(9H-purin-6-ylsulfanyl) Acetohydrazide as Potential Antithyroid Agents

Some novel derivatives of 2-(9H-Purin-6-ylsulfanyl)acetohydrazide were synthesized by reacting it with respective aldehydes in ethanol. The antithyroid effect of these compounds was ascertained in vitro by studying their complexation with iodine spectrophotometrically. In vivo, the hormonal as well...

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Publicat a:Journal of the Mexican Chemical Society
Autors principals: Ismat Fatima, Munawar A. Munawar, Waqar Nasir, Misbahul A. Khan, Affia Tasneem, Tauqir Fatima, Muhammad R. Adil
Format: Artigo
Idioma:Inglês
Publicat: Sociedad Química de México 2012
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Accés en línia:https://www.redalyc.org/articulo.oa?id=47525153002
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