Toxicological Evaluation of Anti-Scrapie Trimethoxychalcones and Oxadiazoles

An altered form of the cellular prion protein, the PrPSc or PrPRes, is implicated in the occurrence of the still untreatable transmissible spongiform encephalopathies. We have previously synthesized and characterized aromatic compounds that inhibit protease-resistant prion protein (PrPRes) accumulat...

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Bibliografski detalji

Izdano u:	Anais da Academia Brasileira de Ciências
Glavni autori:	Claudia P. Figueiredo, Natalia C. Ferreira, Giselle F. Passos, Robson da Costa, Fernanda S. Neves, Clarice S.C. Machado, Alessandra Mascarello, Louise D. Chiaradia-Delatorre, Patrícia D. Neuenfeldt, Ricardo J. Nunes, Yraima Cordeiro
Format:	Artigo
Jezik:	Inglês
Izdano:	Academia Brasileira de Ciências 2015
Teme:	Multidisciplinaria (Ciencias Naturales y Exactas)
Online pristup:	https://www.redalyc.org/articulo.oa?id=32742178013
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