Toxicological Evaluation of Anti-Scrapie Trimethoxychalcones and Oxadiazoles
An altered form of the cellular prion protein, the PrPSc or PrPRes, is implicated in the occurrence of the still untreatable transmissible spongiform encephalopathies. We have previously synthesized and characterized aromatic compounds that inhibit protease-resistant prion protein (PrPRes) accumulat...
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| Gepubliceerd in: | Anais da Academia Brasileira de Ciências |
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| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Academia Brasileira de Ciências
2015
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| Onderwerpen: | |
| Online toegang: | https://www.redalyc.org/articulo.oa?id=32742178013 |
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