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Preparation of a working seed lot of BCG and quality control by PCR genotyping

The bacillus Calmette-Guérin (BCG) was obtained in 1920 after successive passages leading to the attenuation of a Mycobacterium bovis strain. For the following 40 years, BCG had been replicated, resulting in substrains with genotypic and phenotypic differences. Several genomic studies have compared...

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Detalhes bibliográficos
Publicado no:Revista Argentina de Microbiología
Main Authors: A. TROVERO, C. ARGÜELLES, A. CATALDI
Formato: Artigo
Idioma:Inglês
Publicado em: Asociación Argentina de Microbiología 2010
Assuntos:
PCR
Acesso em linha:https://www.redalyc.org/articulo.oa?id=213014884002
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