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Preparation of a working seed lot of BCG and quality control by PCR genotyping
The bacillus Calmette-Guérin (BCG) was obtained in 1920 after successive passages leading to the attenuation of a Mycobacterium bovis strain. For the following 40 years, BCG had been replicated, resulting in substrains with genotypic and phenotypic differences. Several genomic studies have compared...
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Publicado no: | Revista Argentina de Microbiología |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Asociación Argentina de Microbiología
2010
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Assuntos: | |
Acesso em linha: | https://www.redalyc.org/articulo.oa?id=213014884002 |
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