Loss of mRor1 Enhances the Heart and Skeletal Abnormalities in mRor2-Deficient Mice: Redundant and Pleiotropic Functions of mRor1 and mRor2 Receptor Tyrosine Kinases

The mammalian Ror family of receptor tyrosine kinases consists of two structurally related proteins, Ror1 and Ror2. We have shown that mRor2-deficient mice exhibit widespread skeletal abnormalities, ventricular septal defects in the heart, and respiratory dysfunction, leading to neonatal lethality (...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Nomi, Masashi, Oishi, Isao, Kani, Shuichi, Suzuki, Hiroaki, Matsuda, Takeru, Yoda, Akinori, Kitamura, Makiko, Itoh, Kyoko, Takeuchi, Shigeto, Takeda, Kiyoshi, Akira, Shizuo, Ikeya, Makoto, Takada, Shinji, Minami, Yasuhiro
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99997/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11713269/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.24.8329-8335.2001
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!