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Structure-Function Analysis of Lyn Kinase Association with Lipid Rafts and Initiation of Early Signaling Events after Fcɛ Receptor I Aggregation

The first step in immunoreceptor signaling is represented by ligand-dependent receptor aggregation, followed by receptor phosphorylation mediated by tyrosine kinases of the Src family. Recently, sphingolipid- and cholesterol-rich plasma membrane microdomains, called lipid rafts, have been identified...

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Главные авторы: Kovářová, Martina, Tolar, Pavel, Arudchandran, Ramachandran, Dráberová, Lubica, Rivera, Juan, Dráber, Petr
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC99996/
https://ncbi.nlm.nih.gov/pubmed/11713268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8318-8328.2001
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