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Resistance to Tumor Necrosis Factor-Induced Cell Death Mediated by PMCA4 Deficiency
We used retrovirus insertion-mediated random mutagenesis to generate tumor necrosis factor (TNF)-resistant lines from L929 cells. Using this approach, we discovered that the plasma membrane calcium ATPase 4 (PMCA4) is required for TNF-induced cell death in L929 cells. Under basal conditions, PMCA4-d...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC99993/ https://ncbi.nlm.nih.gov/pubmed/11713265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8276-8288.2001 |
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