Mechanisms of CAS Substrate Domain Tyrosine Phosphorylation by FAK and Src

Tyrosine phosphorylation of CAS (Crk-associated substrate, p130(Cas)) has been implicated as a key signaling step in integrin control of normal cellular behaviors, including motility, proliferation, and survival. Aberrant CAS tyrosine phosphorylation may contribute to cell transformation by certain...

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Bibliographic Details
Main Authors: Ruest, Paul J., Shin, Nah-Young, Polte, Thomas R., Zhang, Xiaoe, Hanks, Steven K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC99935/
https://ncbi.nlm.nih.gov/pubmed/11604500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.22.7641-7652.2001
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