The Transcription Elongation Factor CA150 Interacts with RNA Polymerase II and the Pre-mRNA Splicing Factor SF1

CA150 represses RNA polymerase II (RNAPII) transcription by inhibiting the elongation of transcripts. The FF repeat domains of CA150 bind directly to the phosphorylated carboxyl-terminal domain of the largest subunit of RNAPII. We determined that this interaction is required for efficient CA150-medi...

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Main Authors: Goldstrohm, Aaron C., Albrecht, Todd R., Suñé, Carles, Bedford, Mark T., Garcia-Blanco, Mariano A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC99933/
https://ncbi.nlm.nih.gov/pubmed/11604498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.22.7617-7628.2001
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