Human T-Cell Lymphotropic Virus Type 1 Tax Represses c-Myb-Dependent Transcription through Activation of the NF-κB Pathway and Modulation of Coactivator Usage

The proto-oncogene c-myb is essential for a controlled balance between cell growth and differentiation. Aberrant c-Myb activity has been reported for numerous human cancers, and enforced c-Myb transcription can transform cells of lymphoid origin by stimulating cellular proliferation and inhibiting a...

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Detalhes bibliográficos
Main Authors: Nicot, Christophe, Mahieux, Renaud, Pise-Masison, Cynthia, Brady, John, Gessain, Antoine, Yamaoka, Shoji, Franchini, Genoveffa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99912/
https://ncbi.nlm.nih.gov/pubmed/11585920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.21.7391-7402.2001
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