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Raf Kinase Inhibitor Protein Interacts with NF-κB-Inducing Kinase and TAK1 and Inhibits NF-κB Activation

The Raf kinase inhibitor protein (RKIP) acts as a negative regulator of the mitogen-activated protein (MAP) kinase (MAPK) cascade initiated by Raf-1. RKIP inhibits the phosphorylation of MAP/extracellular signal-regulated kinase 1 (MEK1) by Raf-1 by disrupting the interaction between these two kinas...

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Udgivet i:Mol Cell Biol
Principais autores: Yeung, Kam C., Rose, David W., Dhillon, Amardeep S., Yaros, Diane, Gustafsson, Marcus, Chatterjee, Devasis, McFerran, Brian, Wyche, James, Kolch, Walter, Sedivy, John M.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99896/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11585904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.21.7207-7217.2001
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