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MEKK1 Is Essential for DT40 Cell Apoptosis in Response to Microtubule Disruption

Vinblastine and other microtubule-damaging agents, such as nocodazole and paclitaxel, cause cell cycle arrest at the G(2)/M transition and promote apoptosis in eukaryotic cells. The roles of these drugs in disrupting microtubule dynamics and causing cell cycle arrest are well characterized. However,...

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Detalhes bibliográficos
Main Authors: Kwan, Raymond, Burnside, Joan, Kurosaki, Tomohiro, Cheng, Genhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99893/
https://ncbi.nlm.nih.gov/pubmed/11585901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.21.7183-7190.2001
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