Topoisomerase III Acts Upstream of Rad53p in the S-Phase DNA Damage Checkpoint

Deletion of the Saccharomyces cerevisiae TOP3 gene, encoding Top3p, leads to a slow-growth phenotype characterized by an accumulation of cells with a late S/G(2) content of DNA (S. Gangloff, J. P. McDonald, C. Bendixen, L. Arthur, and R. Rothstein, Mol. Cell. Biol. 14:8391–8398, 1994). We have inves...

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Bibliografske podrobnosti
Main Authors: Chakraverty, Ronjon K., Kearsey, Jonathan M., Oakley, Thomas J., Grenon, Muriel, de la Torre Ruiz, Maria-Angeles, Lowndes, Noel F., Hickson, Ian D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
DNA Dynamics and Chromosome Structure
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC99890/
https://ncbi.nlm.nih.gov/pubmed/11585898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.21.7150-7162.2001
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