The Mechanism of Mus81-Mms4 Cleavage Site Selection Distinguishes It from the Homologous Endonuclease Rad1-Rad10

Mus81-Mms4 and Rad1-Rad10 are homologous structure-specific endonucleases that cleave 3′ branches from distinct substrates and are required for replication fork stability and nucleotide excision repair, respectively, in the yeast Saccharomyces cerevisiae. We explored the basis of this biochemical an...

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Autors principals: Bastin-Shanower, Suzanne A., Fricke, William M., Mullen, Janet R., Brill, Steven J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
DNA Dynamics and Chromosome Structure
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164751/
https://ncbi.nlm.nih.gov/pubmed/12724407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3487-3496.2003
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