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The Mechanism of Mus81-Mms4 Cleavage Site Selection Distinguishes It from the Homologous Endonuclease Rad1-Rad10

Mus81-Mms4 and Rad1-Rad10 are homologous structure-specific endonucleases that cleave 3′ branches from distinct substrates and are required for replication fork stability and nucleotide excision repair, respectively, in the yeast Saccharomyces cerevisiae. We explored the basis of this biochemical an...

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Détails bibliographiques
Auteurs principaux: Bastin-Shanower, Suzanne A., Fricke, William M., Mullen, Janet R., Brill, Steven J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC164751/
https://ncbi.nlm.nih.gov/pubmed/12724407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3487-3496.2003
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