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ZAP-70-Independent Ca(2+) Mobilization and Erk Activation in Jurkat T Cells in Response to T-Cell Antigen Receptor Ligation
The tyrosine kinase ZAP-70 has been implicated as a critical intermediary between T-cell antigen receptor (TCR) stimulation and Erk activation on the basis of the ability of dominant negative ZAP-70 to inhibit TCR-stimulated Erk activation, and the reported inability of anti-CD3 antibodies to activa...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC99889/ https://ncbi.nlm.nih.gov/pubmed/11585897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.21.7137-7149.2001 |
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