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Mitogen-Regulated RSK2-CBP Interaction Controls Their Kinase and Acetylase Activities
The protein kinase ribosomal S6 kinase 2 (RSK2) has been implicated in phosphorylation of transcription factor CREB and histone H3 in response to mitogenic stimulation by epidermal growth factor. Binding of phospho-CREB to the coactivator CBP allows gene activation through recruitment of the basal t...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC99884/ https://ncbi.nlm.nih.gov/pubmed/11564891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.20.7089-7096.2001 |
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