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Mitogen-Regulated RSK2-CBP Interaction Controls Their Kinase and Acetylase Activities

The protein kinase ribosomal S6 kinase 2 (RSK2) has been implicated in phosphorylation of transcription factor CREB and histone H3 in response to mitogenic stimulation by epidermal growth factor. Binding of phospho-CREB to the coactivator CBP allows gene activation through recruitment of the basal t...

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Udgivet i:Mol Cell Biol
Principais autores: Merienne, Karine, Pannetier, Solange, Harel-Bellan, Annick, Sassone-Corsi, Paolo
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99884/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11564891/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.20.7089-7096.2001
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