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A 36-Amino-Acid Region of CIITA Is an Effective Inhibitor of CBP: Novel Mechanism of Gamma Interferon-Mediated Suppression of Collagen α(2)(I) and Other Promoters

The class II transactivator (CIITA) is induced by gamma interferon (IFN-γ) and activates major histocompatibility complex class II; however, this report shows it suppresses other genes. An N-terminal 36 amino acids of CIITA mediates suppression of the collagen α(2)(I) promoter via binding to CREB-bi...

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Bibliografske podrobnosti
Main Authors: Zhu, Xin-Sheng, Ting, Jenny P.-Y.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC99883/
https://ncbi.nlm.nih.gov/pubmed/11564890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.20.7078-7088.2001
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