Histone Deacetylase 1/mSin3A Disrupts Gamma Interferon-Induced CIITA Function and Major Histocompatibility Complex Class II Enhanceosome Formation

The class II transactivator (CIITA) is a master transcriptional regulator of major histocompatibility complex class II (MHC-II) promoters. CIITA does not bind DNA, but it interacts with the transcription factors RFX5, NF-Y, and CREB and associated chromatin-modifying enzymes to form an enhanceosome....

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Detalhes bibliográficos
Main Authors: Zika, Eleni, Greer, Susanna F., Zhu, Xin-Sheng, Ting, Jenny P.-Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153210/
https://ncbi.nlm.nih.gov/pubmed/12697811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.9.3091-3102.2003
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