The Sensitivity of Activated Cys Ret Mutants to Glial Cell Line-Derived Neurotrophic Factor Is Mandatory To Rescue Neuroectodermic Cells from Apoptosis

Hirschsprung's disease (HSCR), a frequent developmental defect of the enteric nervous system is due to loss-of-function mutations of RET, a receptor tyrosine kinase essential for the mediation of glial cell-derived neurotrophic factor (GDNF)-induced cell survival. Instead, gain-of-function Cys mutat...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Mograbi, Baharia, Bocciardi, Renata, Bourget, Isabelle, Juhel, Thierry, Farahi-Far, Dariush, Romeo, Giovanni, Ceccherini, Isabella, Rossi, Bernard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99850/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11564857/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.20.6719-6730.2001
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