The Sensitivity of Activated Cys Ret Mutants to Glial Cell Line-Derived Neurotrophic Factor Is Mandatory To Rescue Neuroectodermic Cells from Apoptosis

Hirschsprung's disease (HSCR), a frequent developmental defect of the enteric nervous system is due to loss-of-function mutations of RET, a receptor tyrosine kinase essential for the mediation of glial cell-derived neurotrophic factor (GDNF)-induced cell survival. Instead, gain-of-function Cys mutat...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Mograbi, Baharia, Bocciardi, Renata, Bourget, Isabelle, Juhel, Thierry, Farahi-Far, Dariush, Romeo, Giovanni, Ceccherini, Isabella, Rossi, Bernard
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2001
Fag:	Cell Growth and Development
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99850/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11564857/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.20.6719-6730.2001
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!