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Definition of the minimal viral components required for the initiation of unprimed RNA synthesis by influenza virus RNA polymerase

The first 11 nt at the 5′ end of influenza virus genomic RNA were shown to be both necessary and sufficient for specific binding by the influenza virus polymerase. A novel in vitro transcription assay, in which the polymerase was bound to paramagnetic beads via a biotinylated 5′-vRNA oligonucleotide...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Lee, M. T. Michael, Bishop, Konrad, Medcalf, Liz, Elton, Debra, Digard, Paul, Tiley, Laurence
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99831/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11788704/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.2.429
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