Definition of the minimal viral components required for the initiation of unprimed RNA synthesis by influenza virus RNA polymerase

The first 11 nt at the 5′ end of influenza virus genomic RNA were shown to be both necessary and sufficient for specific binding by the influenza virus polymerase. A novel in vitro transcription assay, in which the polymerase was bound to paramagnetic beads via a biotinylated 5′-vRNA oligonucleotide...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Lee, M. T. Michael, Bishop, Konrad, Medcalf, Liz, Elton, Debra, Digard, Paul, Tiley, Laurence
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 2002
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99831/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11788704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.2.429
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