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B-Cell Receptor- and Phorbol Ester-Induced NF-κB and c-Jun N-Terminal Kinase Activation in B Cells Requires Novel Protein Kinase C's

Antigen receptor signaling is known to activate NF-κB in lymphocytes. While T-cell-receptor-induced NF-κB activation critically depends on novel protein kinase C θ (PKCθ), the role of novel PKCs in B-cell stimulation has not been elucidated. In primary murine splenic B cells, we found high expressio...

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Detalles Bibliográficos
Main Authors: Krappmann, Daniel, Patke, Alina, Heissmeyer, Vigo, Scheidereit, Claus
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC99809/
https://ncbi.nlm.nih.gov/pubmed/11533251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.19.6640-6650.2001
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