Creation of a Pluripotent Ubiquitin-Conjugating Enzyme

We describe the creation of a pluripotent ubiquitin-conjugating enzyme (E2) generated through a single amino acid substitution within the catalytic domain of RAD6 (UBC2). This RAD6 derivative carries out the stress-related function of UBC4 and the cell cycle function of CDC34 while maintaining its o...

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Detalhes bibliográficos
Main Authors: Ptak, Christopher, Gwozd, Chantelle, Huzil, J. Torin, Gwozd, Todd J., Garen, Grace, Ellison, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99800/
https://ncbi.nlm.nih.gov/pubmed/11533242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.19.6537-6548.2001
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