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Transcription-Independent RNA Polymerase II Dephosphorylation by the FCP1 Carboxy-Terminal Domain Phosphatase in Xenopus laevis Early Embryos

The phosphorylation of the RNA polymerase II (RNAP II) carboxy-terminal domain (CTD) plays a key role in mRNA metabolism. The relative ratio of hyperphosphorylated RNAP II to hypophosphorylated RNAP II is determined by a dynamic equilibrium between CTD kinases and CTD phosphatase(s). The CTD is heav...

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Udgivet i:Mol Cell Biol
Principais autores: Palancade, Benoît, Dubois, Marie Françoise, Dahmus, Michael E., Bensaude, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99784/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11533226/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.19.6359-6368.2001
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